HRT basics, without the fear
A calm, current-evidence primer on hormone therapy — what it is, who it's for, and the questions to bring to your clinician.
These guides are written by Grace, your Menofly AI companion, and fact-checked against published research and clinical sources. This content is for educational purposes and is not a substitute for medical advice.
Reset the frame
The 2002 Women's Health Initiative study led an entire generation of women — and doctors — to fear hormone therapy. The re-analyses that followed painted a very different picture: for most women starting within 10 years of menopause, HRT is one of the most effective and safest tools we have for symptoms and long-term bone protection.
The two components
Estrogen (patch, gel, or spray) treats vasomotor symptoms and protects bone. Progesterone (usually oral, at night) is added if you have a uterus, to protect the lining. Testosterone is sometimes added for libido.
Questions to bring to your clinician
- Given my history and symptoms, what's the case for and against transdermal estrogen for me?
- What's my cardiovascular and breast risk profile — and how does that change the calculus?
- If we start, what's the follow-up cadence? What would make us stop?
- Are there non-hormonal options I should know about — SSRIs, gabapentin, fezolinetant?
Menofly is not going to make this decision with you — no app should. But we will help you show up prepared with 60 days of data and a written list.
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